Early, but not late therapy with a vasopressin V1a-antagonist ameliorates the development of renal damage after 5/6 nephrectomy

Introduction. Vasopressin, mainly through the V 1a -receptor, is thought to be a major player in the maintenance of hyperfiltration. Its inhibition could therefore lead to a decrease in progression of chronic renal failure.To this end, the effect of the vasopressin V1a-receptor-selective antagonist,...

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Bibliographic Details
Main Authors: Willemijn AKM Windt, Atsua Tahara, Alex CA Kluppel, Dick de Zeeuw, Robert H Henning, Richard PE van Dokkum
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2006-12-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.3317/jraas.2006.041