Drosophila signal peptidase complex member Spase12 is required for development and cell differentiation.

It is estimated that half of all proteins expressed in eukaryotic cells are transferred across or into at least one cellular membrane to reach their functional location. Protein translocation into the endoplasmic reticulum (ER) is critical to the subsequent localization of secretory and transmembran...

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Bibliographic Details
Main Authors: Erin Haase Gilbert, Su-Jin Kwak, Rui Chen, Graeme Mardon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3616019?pdf=render