The role of single nucleotide polymorphism of IL-6 and IL-10 cytokine on pain severity and pain relief after radiotherapy in multiple myeloma patients with painful bone destructions

The role of single nucleotide polymorphism of IL-6 and IL-10 cytokine on pain severity and pain relief after radiotherapy in multiple myeloma patients with painful bone destructions

Multiple myeloma (MM) cells interact with bone marrow stromal cells stimulating transcription and secretion of cytokines like IL-6 and IL-10, which are implicated in the progression and dissemination of MM. Regulation of cytokines secretion is under genetic control through genetic polymorph...

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Bibliographic Details
Main Authors: Rudzianskiene Milda, Inciura Arturas, Juozaityte Elona, Gerbutavicius Rolandas, Simoliuniene Renata, Ugenskiene Rasa, Raulinaityte Danguole, Rudzianskas Viktoras, Kiavialaitis Greta Emilia
Format: Article
Language:English
Published: Serbian Genetics Society 2014-01-01
Series:Genetika
Subjects:
Multiple myeloma
single gene polymorphism
pain relief
Online Access:http://www.doiserbia.nb.rs/img/doi/0534-0012/2014/0534-00121402455R.pdf

Internet

http://www.doiserbia.nb.rs/img/doi/0534-0012/2014/0534-00121402455R.pdf

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