MicroRNA Processing and Human Cancer

MicroRNAs (miRNAs) are short non-coding RNAs of 20 to 25 nucleotides that regulate gene expression post-transcriptionally mainly by binding to a specific sequence of the 3′ end of the untranslated region (3′UTR) of target genes. Since the first report on the clinical relevance of miRNAs in cancer, m...

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Bibliographic Details
Main Authors: Masahisa Ohtsuka, Hui Ling, Yuichiro Doki, Masaki Mori, George Adrian Calin
Format: Article
Language:English
Published: MDPI AG 2015-08-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:http://www.mdpi.com/2077-0383/4/8/1651