The secretory pathway calcium ATPase PMR-1/SPCA1 has essential roles in cell migration during Caenorhabditis elegans embryonic development.

The secretory pathway calcium ATPase PMR-1/SPCA1 has essential roles in cell migration during Caenorhabditis elegans embryonic development.

Maintaining levels of calcium in the cytosol is important for many cellular events, including cell migration, where localized regions of high calcium are required to regulate cytoskeletal dynamics, contractility, and adhesion. Studies show inositol-trisphosphate receptors (IP3R) and ryanodine recept...

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Bibliographic Details
Main Authors: Vida Praitis, Jeffrey Simske, Sarah Kniss, Rebecca Mandt, Leah Imlay, Charlotte Feddersen, Michael B Miller, Juliet Mushi, Walter Liszewski, Rachel Weinstein, Adityarup Chakravorty, Dae-Gon Ha, Angela Schacht Farrell, Alexander Sullivan-Wilson, Tyson Stock
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-05-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3656159?pdf=render

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http://europepmc.org/articles/PMC3656159?pdf=render

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