Tissue engineering and regenerative approaches to improving the healing of large bone defects

Tissue engineering and regenerative approaches to improving the healing of large bone defects

Despite the high innate regenerative capacity of bone, large osseous defects fail to heal and remain a clinical challenge. Healing such defects requires the formation of large amounts of bone in an environment often rendered hostile to osteogenesis by damage to the surrounding soft tissues and vascu...

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Bibliographic Details
Main Authors: S Verrier, M Alini, E Alsberg, SR Buchman, D Kelly, MW Laschke, MD Menger, WL Murphy, JP Stegemann, M Schütz, T Miclau, MJ Stoddart, C Evans
Format: Article
Language:English
Published: AO Research Institute Davos 2016-07-01
Series:European Cells & Materials
Subjects:
Bone
vascularisation
scaffolds
gene therapy
stem cells
drug delivery
large bone defect
tissue engineering
regenerative medicine
translational and preclinical research
Online Access:http://www.ecmjournal.org/papers/vol032/pdf/v032a06.pdf

Internet

http://www.ecmjournal.org/papers/vol032/pdf/v032a06.pdf

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