The lysolipid transporter Mfsd2a regulates lipogenesis in the developing brain.
Brain development requires a massive increase in brain lipogenesis and accretion of the essential omega-3 fatty acid docosahexaenoic acid (DHA). Brain acquisition of DHA is primarily mediated by the transporter Major Facilitator Superfamily Domain containing 2a (Mfsd2a) expressed in the endothelium...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2018-08-01
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Series: | PLoS Biology |
Online Access: | https://doi.org/10.1371/journal.pbio.2006443 |