The lysolipid transporter Mfsd2a regulates lipogenesis in the developing brain.

The lysolipid transporter Mfsd2a regulates lipogenesis in the developing brain.

Brain development requires a massive increase in brain lipogenesis and accretion of the essential omega-3 fatty acid docosahexaenoic acid (DHA). Brain acquisition of DHA is primarily mediated by the transporter Major Facilitator Superfamily Domain containing 2a (Mfsd2a) expressed in the endothelium...

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Bibliographic Details
Main Authors: Jia Pei Chan, Bernice H Wong, Cheen Fei Chin, Dwight L A Galam, Juat Chin Foo, Loo Chin Wong, Sujoy Ghosh, Markus R Wenk, Amaury Cazenave-Gassiot, David L Silver
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-08-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.2006443

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https://doi.org/10.1371/journal.pbio.2006443

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