Metformin and Ara-a Effectively Suppress Brain Cancer by Targeting Cancer Stem/Progenitor Cells

Metformin and Ara-a Effectively Suppress Brain Cancer by Targeting Cancer Stem/Progenitor Cells

Background: Gliomas and neuroblastomas pose a great health burden worldwide with a poor and moderate prognosis, respectively. Many studies have tried to find effective treatments for these primary malignant brain tumors. Of interest, the AMP-activated protein kinase (AMPK) pathway was found to be as...

Full description

Bibliographic Details
Main Authors: Tarek H. Mouhieddine, Amaly eNokkari, Muhieddine M Itani, Farah eChamaa, Hisham eBahmad, Alissar eMonzer, Rabih eEl-Merahbi, Georges eDaoud, Assaad eEid, Firas H Kobeissy, Wassim eAbou-Kheir
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-11-01
Series:Frontiers in Neuroscience
Subjects:
Glioblastoma
Metformin
Neuroblastoma
Cancer stem cell
Ara-A
AMPK pathway
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2015.00442/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnins.2015.00442/full

Similar Items