C. elegans germ cells switch between distinct modes of double-strand break repair during meiotic prophase progression.
Chromosome inheritance during sexual reproduction relies on deliberate induction of double-strand DNA breaks (DSBs) and repair of a subset of these breaks as interhomolog crossovers (COs). Here we provide a direct demonstration, based on our analysis of rad-50 mutants, that the meiotic program in Ca...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2007-11-01
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| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC2048528?pdf=render |