PPARα controls the intracellular coenzyme A concentration via regulation of PANK1α gene expression1

PPARα controls the intracellular coenzyme A concentration via regulation of PANK1α gene expression1

Pantothenate kinase (PanK) is thought to catalyze the first rate-limiting step in CoA biosynthesis. The full-length cDNA encoding the human PanK1α protein was isolated, and the complete human PANK1 gene structure was determined. Bezafibrate (BF), a hypolipidemic drug and a peroxisome proliferator ac...

Full description

Bibliographic Details
Main Authors: Gayathri Ramaswamy, Mohammad A. Karim, K. Gopal Murti, Suzanne Jackowski
Format: Article
Language:English
Published: Elsevier 2004-01-01
Series:Journal of Lipid Research
Subjects:
pantothenate
pantothenate kinase
peroxisome proliferator activator receptor-α
fatty acid β-oxidation
liver
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520319179

Internet

http://www.sciencedirect.com/science/article/pii/S0022227520319179

Similar Items