Solid-phase-supported synthesis of morpholinoglycine oligonucleotide mimics

Solid-phase-supported synthesis of morpholinoglycine oligonucleotide mimics

An efficient solid-phase-supported peptide synthesis (SPPS) of morpholinoglycine oligonucleotide (MorGly) mimics has been developed. The proposed strategy includes a novel specially designed labile linker group containing the oxalyl residue and the 2-aminomethylmorpholino nucleoside analogues as fir...

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Bibliographic Details
Main Authors: Tatyana V. Abramova, Sergey S. Belov, Yulia V. Tarasenko, Vladimir N. Silnikov
Format: Article
Language:English
Published: Beilstein-Institut 2014-05-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
labile linker
morpholino oligomers
oligonucleotide mimics
solid-phase-supported peptide synthesis (SPPS)
Online Access:https://doi.org/10.3762/bjoc.10.115

Internet

https://doi.org/10.3762/bjoc.10.115

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