BRCA1, BRCA2 and primary ovarian insufficiency
BRCA1 and BRCA2 genes belong to the family of ataxia-telangiectasia-mutated (ATM)-mediated DNA DSB repair genes that play a critical role in the DNA double-strand break (DSB) repair. Mutations in BRCA genes significantly increase the lifetime risk of breast, ovarian, fallopian tube and primary perit...
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Format: | Article |
Language: | English |
Published: |
EDP Sciences
2020-01-01
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Series: | E3S Web of Conferences |
Online Access: | https://www.e3s-conferences.org/articles/e3sconf/pdf/2020/25/e3sconf_caes2020_05009.pdf |