Therapeutic Effect of Losartan, an Angiotensin II Type 1 Receptor Antagonist, on CCl4-Induced Skeletal Muscle Injury

TGF-β1 is known to inhibit muscle regeneration after muscle injury. However, it is unknown if high systemic levels of TGF-β can affect the muscle regeneration process. In the present study, we demonstrated the effect of a CCl4 intra-peritoneal injection and losartan (an angiotensin II type 1 recepto...

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Bibliographic Details
Main Authors: Ok-Kyung Hwang, Jin-Kyu Park, Eun-Joo Lee, Eun-Mi Lee, Ah-Young Kim, Kyu-Shik Jeong
Format: Article
Language:English
Published: MDPI AG 2016-02-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/17/2/227