Pyrimidine Acyclo-C-Nucleosides by Ring Transformations of 2-Formyl-L-arabinal

Pyrimidine Acyclo-C-Nucleosides by Ring Transformations of 2-Formyl-L-arabinal

The protected 2-formyl-L-arabinal 2 reacted with thiourea and cyanamide in the presence of sodium hydride to afford via ring transformations the 5-[1R,2S-1,2- bis(benzyloxy)-3-hydroxypropyl]-1,2-dihydropyrimidines 3 and 4, respectively. Similarly, treatment of 2 with 3-amino-2H-1,2,4-triazole yielde...

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Bibliographic Details
Main Authors: Klaus Peseke, Manfred Michalik, Holger Feist, Ahmed Bari
Format: Article
Language:English
Published: MDPI AG 2005-08-01
Series:Molecules
Subjects:
Glycals
nucleoside analogues
pyrimidines
fused pyrimidines
push-pull alkenes
ring transformation
Online Access:http://www.mdpi.com/1420-3049/10/8/837/

Internet

http://www.mdpi.com/1420-3049/10/8/837/

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