Allograft or Recipient ST2 Deficiency Oppositely Affected Cardiac Allograft Vasculopathy via Differentially Altering Immune Cells Infiltration

Allograft or Recipient ST2 Deficiency Oppositely Affected Cardiac Allograft Vasculopathy via Differentially Altering Immune Cells Infiltration

The role of IL-33/ST2 signaling in cardiac allograft vasculopathy (CAV) is not fully addressed. Here, we investigated the role of IL-33/ST2 signaling in allograft or recipient in CAV respectively using MHC-mismatch murine chronic cardiac allograft rejection model. We found that recipients ST2 defici...

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Bibliographic Details
Main Authors: Zhenggang Zhang, Na Zhang, Junyu Shi, Chan Dai, Suo Wu, Mengya Jiao, Xuhuan Tang, Yunfei Liu, Xiaoxiao Li, Yong Xu, Zheng Tan, Feili Gong, Fang Zheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Immunology
Subjects:
IL-33
ST2
heart transplantation
cardiac allograft vasculopathy
chronic rejection
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.657803/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.657803/full

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