Effect of Xiaoyaosan on Colon Morphology and Intestinal Permeability in Rats With Chronic Unpredictable Mild Stress

Effect of Xiaoyaosan on Colon Morphology and Intestinal Permeability in Rats With Chronic Unpredictable Mild Stress

PurposeIn our present study, a rat depression model induced by 6 weeks of chronic unpredictable mild stress (CUMS) was established, and we investigated how Xiaoyaosan affects the intestinal permeability of depressed rats and alterations in tight-junction proteins (TJs) involved in this process.Metho...

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Bibliographic Details
Main Authors: Fengmin Ding, Jiajia Wu, Chenyue Liu, Qinglai Bian, Wenqi Qiu, Qingyu Ma, Xiaojuan Li, Man Long, Xiaojuan Zou, Jiaxu Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Pharmacology
Subjects:
chronic unpredictable mild stress
intestinal permeability
Xiaoyaosan
tight junction protein
5-HT
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.01069/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.01069/full

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