Spatiotemporal mapping of RNA editing in the developing mouse brain using in situ sequencing reveals regional and cell-type-specific regulation

Spatiotemporal mapping of RNA editing in the developing mouse brain using in situ sequencing reveals regional and cell-type-specific regulation

Abstract Background Adenosine-to-inosine (A-to-I) RNA editing is a process that contributes to the diversification of proteins that has been shown to be essential for neurotransmission and other neuronal functions. However, the spatiotemporal and diversification properties of RNA editing in the brai...

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Bibliographic Details
Main Authors: Elin Lundin, Chenglin Wu, Albin Widmark, Mikaela Behm, Jens Hjerling-Leffler, Chammiran Daniel, Marie Öhman, Mats Nilsson
Format: Article
Language:English
Published: BMC 2020-01-01
Series:BMC Biology
Subjects:
Single-cell resolution
RNA editing
Spatially resolved transcriptomics
Brain development
Online Access:https://doi.org/10.1186/s12915-019-0736-3

Internet

https://doi.org/10.1186/s12915-019-0736-3

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