ING3 promotes prostate cancer growth by activating the androgen receptor

Abstract Background The androgen receptor (AR) is a major driver of prostate cancer, and increased AR levels and co-activators of the receptor promote the development of prostate cancer. INhibitor of Growth (ING) proteins target lysine acetyltransferase or lysine deacetylase complexes to the histone...

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Bibliographic Details
Main Authors: Arash Nabbi, Urszula L. McClurg, Subhash Thalappilly, Amal Almami, Mahsa Mobahat, Tarek A. Bismar, Olivier Binda, Karl T. Riabowol
Format: Article
Language:English
Published: BMC 2017-05-01
Series:BMC Medicine
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12916-017-0854-0