Puumala and Tula Virus Differ in Replication Kinetics and Innate Immune Stimulation in Human Endothelial Cells and Macrophages

Old world hantaviruses cause hemorrhagic fever with renal syndrome (HFRS) upon zoonotic transmission to humans. In Europe, the Puumala virus (PUUV) is the main causative agent of HFRS. Tula virus (TULV) is also widely distributed in Europe, but there is little knowledge about the pathogenicity of TU...

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Bibliographic Details
Main Authors: Daniel Bourquain, Clemens Bodenstein, Stefanie Schürer, Lars Schaade
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/11/9/855