Synthesis of crocetin derivatives and their potent inhibition in multiple tumor cells proliferation and inflammatory property of macrophage

Synthesis of crocetin derivatives and their potent inhibition in multiple tumor cells proliferation and inflammatory property of macrophage

Abstract Background Crocetin is a major active component of saffron, which has a wide range of pharmacological effects. However, due to its low solubility, the pharmacological effects of crocetin cannot be better utilized. Methods In this study, we modified the chemical structure of crocetin by conj...

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Bibliographic Details
Main Authors: Mao-Ze Wang, Jin Gao, Yang Chu, Jie Niu, Ming Chen, Qiang Shang, Li-Hua Peng, Zhi-Hong Jiang
Format: Article
Language:English
Published: BMC 2020-02-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Solubility
Crocetin derivatives
Anti-tumor effect
Inflammation inhibition
Online Access:https://doi.org/10.1186/s12906-020-2831-y

Internet

https://doi.org/10.1186/s12906-020-2831-y

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