TIFAB Regulates USP15-Mediated p53 Signaling during Stressed and Malignant Hematopoiesis

TIFAB Regulates USP15-Mediated p53 Signaling during Stressed and Malignant Hematopoiesis

Summary: TRAF-interacting protein with a forkhead-associated domain B (TIFAB) is implicated in myeloid malignancies with deletion of chromosome 5q. Employing a combination of proteomic and genetic approaches, we find that TIFAB regulates ubiquitin-specific peptidase 15 (USP15) ubiquitin hydrolase ac...

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Bibliographic Details
Main Authors: Madeline Niederkorn, Kathleen Hueneman, Kwangmin Choi, Melinda E. Varney, Laurel Romano, Mario A. Pujato, Kenneth D. Greis, Jun-ichiro Inoue, Ruhikanta Meetei, Daniel T. Starczynowski
Format: Article
Language:English
Published: Elsevier 2020-02-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720301273

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http://www.sciencedirect.com/science/article/pii/S2211124720301273

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