Characterization by Nano-Infrared Spectroscopy of Individual Aggregated Species of Amyloid Proteins

Characterization by Nano-Infrared Spectroscopy of Individual Aggregated Species of Amyloid Proteins

Amyloid fibrils are composed of aggregated peptides or proteins in a fibrillar structure with a higher β-sheet content than in their native structure. To characterize them, we used an innovative tool that coupled infrared spectroscopy with atomic force microscopy (AFM-IR). With this method, we show...

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Bibliographic Details
Main Authors: Jehan Waeytens, Vincent Van Hemelryck, Ariane Deniset-Besseau, Jean-Marie Ruysschaert, Alexandre Dazzi, Vincent Raussens
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Molecules
Subjects:
amyloid fibrils
aggregated species
oligomers
photothermal infrared nanospectroscopy
AFM-IR
Online Access:https://www.mdpi.com/1420-3049/25/12/2899

Internet

https://www.mdpi.com/1420-3049/25/12/2899

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