Arbutin effectively ameliorates the symptoms of Parkinson’s disease: the role of adenosine receptors and cyclic adenosine monophosphate

Arbutin effectively ameliorates the symptoms of Parkinson’s disease: the role of adenosine receptors and cyclic adenosine monophosphate

An antagonistic communication exists between adenosinergic and dopaminergic signaling in the basal ganglia, which suggests that the suppression of adenosine A2A receptors-cyclic adenosine monophosphate pathway may be able to restore the disrupted dopamine transmission that results in motor symptoms...

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Bibliographic Details
Main Authors: Jie Zhao, Manish Kumar, Jeevan Sharma, Zhihai Yuan
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Neural Regeneration Research
Subjects:
arbutin; cgs21680; dopamine; forskolin; gaba; inflammation; oxidative stress; parkinson’s disease; striatum; substantia nigra
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2021;volume=16;issue=10;spage=2030;epage=2040;aulast=Zhao

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2021;volume=16;issue=10;spage=2030;epage=2040;aulast=Zhao

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