Targeting cell cycle regulators in hematologic malignancies

Hematologic malignancies represent the fourth most frequently diagnosed cancer in economically developed countries. In hematologic malignancies normal hematopoiesis is interrupted by uncontrolled growth of a genetically altered stem or progenitor cell (HSPC) that maintains its ability of self-renewa...

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Bibliographic Details
Main Authors: Eiman eAleem, Robert eArceci
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-04-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcell.2015.00016/full