Enhancer of zeste homolog 2 regulates cell differentiation and proliferation in neuroblastoma

Background Neuroblastoma (NB) is one of the most common extracranial solid tumors occurring in infancy and childhood with highly variable outcomes. Polycomb group (PcG) proteins are epigenetic gene silencers. Enhancer of zeste homolog 2 (EZH2) is a member of the polycomb repressor complex 2 (PRC2)...

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Bibliographic Details
Main Authors: Amallia N. Setyawati, Takehiko Kamij
Format: Article
Language:English
Published: Faculty of Medicine Trisakti University 2014-12-01
Series:Universa Medicina
Subjects:
Online Access:http://www.univmed.org/wp-content/uploads/2015/02/amallia.pdf