A Smart Hyperthermia Nanofiber-Platform-Enabled Sustained Release of Doxorubicin and 17AAG for Synergistic Cancer Therapy

A Smart Hyperthermia Nanofiber-Platform-Enabled Sustained Release of Doxorubicin and 17AAG for Synergistic Cancer Therapy

This study demonstrates the rational fabrication of a magnetic composite nanofiber mesh that can achieve mutual synergy of hyperthermia, chemotherapy, and thermo-molecularly targeted therapy for highly potent therapeutic effects. The nanofiber is composed of biodegradable poly(ε-caprolactone) with d...

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Bibliographic Details
Main Authors: Lili Chen, Nanami Fujisawa, Masato Takanohashi, Mazaya Najmina, Koichiro Uto, Mitsuhiro Ebara
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
cancer therapy
hyperthermia
MNPs
DOX
HSPs inhibitor
nanofiber
Online Access:https://www.mdpi.com/1422-0067/22/5/2542

Internet

https://www.mdpi.com/1422-0067/22/5/2542

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