Subtype-associated epigenomic landscape and 3D genome structure in bladder cancer

Subtype-associated epigenomic landscape and 3D genome structure in bladder cancer

Abstract Muscle-invasive bladder cancers are characterized by their distinct expression of luminal and basal genes, which could be used to predict key clinical features such as disease progression and overall survival. Transcriptionally, FOXA1, GATA3, and PPARG are shown to be essential for luminal...

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Bibliographic Details
Main Authors: Tejaswi Iyyanki, Baozhen Zhang, Qixuan Wang, Ye Hou, Qiushi Jin, Jie Xu, Hongbo Yang, Tingting Liu, Xiaotao Wang, Fan Song, Yu Luan, Hironobu Yamashita, Ruby Chien, Huijue Lyu, Lijun Zhang, Lu Wang, Joshua Warrick, Jay D. Raman, Joshua J. Meeks, David J. DeGraff, Feng Yue
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Genome Biology
Online Access:https://doi.org/10.1186/s13059-021-02325-y

Internet

https://doi.org/10.1186/s13059-021-02325-y

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