Advanced lipoxidation end products (ALEs) as RAGE binders: Mass spectrometric and computational studies to explain the reasons why

Advanced Lipoxidation End-products (ALEs) are modified proteins that can act as pathogenic factors in several chronic diseases. Several molecular mechanisms have so far been considered to explain the damaging action of ALEs and among these a pathway involving the receptor for advanced glycation end...

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Bibliographic Details
Main Authors: Marco Mol, Genny Degani, Crescenzo Coppa, Giovanna Baron, Laura Popolo, Marina Carini, Giancarlo Aldini, Giulio Vistoli, Alessandra Altomare
Format: Article
Language:English
Published: Elsevier 2019-05-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231718310218