Epigenetic mechanisms shape the underlining expression regulatory mechanisms of the STAT3 in multiple sclerosis disease

Epigenetic mechanisms shape the underlining expression regulatory mechanisms of the STAT3 in multiple sclerosis disease

Abstract Objectives Immunological tolerance is mediated by CD4+CD25+ regulatory T (Treg) cells. Studies have shown that thymic and peripheral generations of Treg cells depend on the CD28 signaling pathway. T helper 17 (Th17) cells are involved in the pathophysiology of various inflammatory diseases....

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Main Authors: Arezoo Hosseini, Zohreh Babaloo, Tohid Gharibi, Navid Shomali, Faroogh Marofi, Vida Hashemi, Hormoz Ayromlou, Milad Asadi, Shima Rahmani, Saeed Noorolyai, Dariush Shanehbandi, Behzad Baradaran
Format: Article
Language:English
Published: BMC 2020-12-01
Series:BMC Research Notes
Subjects:
STAT3
Multiple sclerosis
Methylation
Iran
Online Access:https://doi.org/10.1186/s13104-020-05427-1

Internet

https://doi.org/10.1186/s13104-020-05427-1

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