Construction and expression of eukaryotic expression vectors of full-length, amino-terminus and carboxyl-terminus Raf gene

Background and objective Raf is a key molecule in the Ras-Raf-MEK-ERK signal transduction pathway and is highly activated in different human carcinomas. However, its biological functions and regulation mechanisms are still unclear. The aims of this study were to construct eukaryotic expression vecto...

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Bibliographic Details
Main Authors: Zhuomin WANG, Jun CHEN, Haisu WAN, Hongyu LIU, Wen ZHU, Wen XIAO, Yu FAN, Yong LI, Liya SUN, Qinghua ZHOU
Format: Article
Language:zho
Published: Chinese Anti-Cancer Association; Chinese Antituberculosis Association 2008-06-01
Series:Chinese Journal of Lung Cancer
Subjects:
Raf
Online Access:http://www.lungca.org/index.php?journal=01&page=article&op=view&path[]=10.3779%2Fj.issn.1009-3419.2008.03.001&path[]=74