Surface Modification of Hemoglobin-Based Oxygen Carriers Reduces Recognition by Haptoglobin, Immunoglobulin, and Hemoglobin Antibodies

Surface Modification of Hemoglobin-Based Oxygen Carriers Reduces Recognition by Haptoglobin, Immunoglobulin, and Hemoglobin Antibodies

Hemoglobin-based oxygen carriers (HBOCs) represent a propitious type of blood substitute to transport oxygen throughout the body while acting as a carrier in biomedical applications. However, HBOCs in blood are recognized and rapidly scavenged by the body’s innate immune systems. To overco...

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Bibliographic Details
Main Authors: Ausanai Prapan, Nittiya Suwannasom, Chiraphat Kloypan, Saranya Chaiwaree, Axel Steffen, Yu Xiong, Ijad Kao, Axel Pruß, Radostina Georgieva, Hans Bäumler
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Coatings
Subjects:
hemoglobin
blood substitute
haptoglobin
serum albumin
immunoglobulin G
hyaluronic acid
Online Access:https://www.mdpi.com/2079-6412/9/7/454

Internet

https://www.mdpi.com/2079-6412/9/7/454

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