A local proinflammatory signalling loop facilitates adverse age-associated arterial remodeling.

A local proinflammatory signalling loop facilitates adverse age-associated arterial remodeling.

The coincidence of vascular smooth muscle cells (VSMC) infiltration and collagen deposition within a diffusely thickened intima is a salient feature of central arterial wall inflammation that accompanies advancing age. However, the molecular mechanisms involved remain undefined.Immunostaining and im...

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Bibliographic Details
Main Authors: Mingyi Wang, Gaia Spinetti, Robert E Monticone, Jing Zhang, James Wu, Liqun Jiang, Benjamin Khazan, Richard Telljohann, Edward G Lakatta
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-02-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3035650?pdf=render

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http://europepmc.org/articles/PMC3035650?pdf=render

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