Connexin43 Inhibition Prevents Human Vein Grafts Intimal Hyperplasia.

Connexin43 Inhibition Prevents Human Vein Grafts Intimal Hyperplasia.

Venous bypass grafts often fail following arterial implantation due to excessive smooth muscle cells (VSMC) proliferation and consequent intimal hyperplasia (IH). Intercellular communication mediated by Connexins (Cx) regulates differentiation, growth and proliferation in various cell types. Microar...

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Bibliographic Details
Main Authors: Alban Longchamp, Florent Allagnat, Florian Alonso, Christopher Kuppler, Céline Dubuis, Charles-Keith Ozaki, James R Mitchell, Scott Berceli, Jean-Marc Corpataux, Sébastien Déglise, Jacques-Antoine Haefliger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4580578?pdf=render

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http://europepmc.org/articles/PMC4580578?pdf=render

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