Bacterial Lipoproteins Induce BAFF Production via TLR2/MyD88/JNK Signaling Pathways in Dendritic Cells

Bacterial Lipoproteins Induce BAFF Production via TLR2/MyD88/JNK Signaling Pathways in Dendritic Cells

B-cell activating factor (BAFF) plays a crucial role in survival, differentiation, and antibody secretion of B cells. Microbial products with B-cell mitogenic properties can indirectly promote expansion and activation of B cells by stimulating accessory cells, such as dendritic cells (DCs), to induc...

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Bibliographic Details
Main Authors: Jintaek Im, Jung Eun Baik, Dongwook Lee, Ok-Jin Park, Dong Hyun Park, Cheol-Heui Yun, Seung Hyun Han
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Immunology
Subjects:
B-cell activating factor (BAFF)
bacterial lipoproteins
Pam3CSK4
bone marrow–derived dendritic cells
TLR2/1
MyD88
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.564699/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.564699/full

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