Transglutaminases Are Active in Perivascular Adipose Tissue

Transglutaminases (TGs) are crosslinking enzymes best known for their vascular remodeling in hypertension. They require calcium to form an isopeptide bond, connecting a glutamine to a protein bound lysine residue or a free amine donor such as norepinephrine (NE) or serotonin (5-HT). We discovered th...

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Bibliographic Details
Main Authors: Alexis N. Orr, Janice M. Thompson, Janae M. Lyttle, Stephanie W. Watts
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
TG2
Online Access:https://www.mdpi.com/1422-0067/22/5/2649