Rat allele variation determines susceptibility to AngII-induced renal damage

Rat allele variation determines susceptibility to AngII-induced renal damage

Introduction : Ace b/l polymorphism in rats is associated with differential tissue angiotensin-converting enzyme (ACE) expression and activity, and susceptibility to renal damage. Same polymorphism was recently found in outbred Wistar rat strain with b allele accounting for higher renal ACE, and pro...

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Bibliographic Details
Main Authors: Jelena Kamilic, Inge Hamming, A Titia Lely, Ron Korstanje, Ute Schulze, Wilfred J Poppinga, Anthony J Turner, Nicola E Clarke, Harry van Goor, Gerjan J Navis
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2011-12-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.1177/1470320311415886

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https://doi.org/10.1177/1470320311415886

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