Tumor Suppressor miR-184 Enhances Chemosensitivity by Directly Inhibiting SLC7A5 in Retinoblastoma

Tumor Suppressor miR-184 Enhances Chemosensitivity by Directly Inhibiting SLC7A5 in Retinoblastoma

The expression patterns and functional roles of miRNAs in retinoblastoma (RB) are poorly understood, especially those involved in chemoresistance. Here, we validated the expression pattern of 20 potential RB-suppressive miRNAs and confirmed that miR-184 is the most significantly decreased miRNA in h...

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Bibliographic Details
Main Authors: Tian-Geng He, Zi-Yun Xiao, Yi-Qiao Xing, Hua-Jing Yang, Hong Qiu, Jian-Bin Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Oncology
Subjects:
miR-184
SLC7A5
apoptosis
cell cycle
chemosensitivity
retinoblastoma
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.01163/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2019.01163/full

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