A Notch-mediated, temporal asymmetry in BMP pathway activation promotes photoreceptor subtype diversification.

Neural progenitors produce neurons whose identities can vary as a function of the time that specification occurs. Here, we describe the heterochronic specification of two photoreceptor (PhR) subtypes in the zebrafish pineal gland. We find that accelerating PhR specification by impairing Notch signal...

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Bibliographic Details
Main Authors: Elise Cau, Brice Ronsin, Laurianne Bessière, Patrick Blader
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.2006250