Transfection efficiency of chitosan and thiolated chitosan in retinal pigment epithelium cells: A comparative study

Objective: Gene therapy relies on efficient vector for a therapeutic effect. Efficient non-viral vectors are sought as an alternative to viral vectors. Chitosan, a cationic polymer, has been studied for its gene delivery potential. In this work, disulfide bond containing groups were covalently added...

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Bibliographic Details
Main Authors: Ana V Oliveira, Andreia P Silva, Diogo B Bitoque, Gabriela A Silva, Ana M Rosa da Costa
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2013-01-01
Series:Journal of Pharmacy and Bioallied Sciences
Subjects:
Online Access:http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2013;volume=5;issue=2;spage=111;epage=118;aulast=Oliveira