lncRNA UCA1-Mediated Cdc42 Signaling Promotes Oncolytic Vaccinia Virus Cell-to-Cell Spread in Ovarian Cancer

lncRNA UCA1-Mediated Cdc42 Signaling Promotes Oncolytic Vaccinia Virus Cell-to-Cell Spread in Ovarian Cancer

Oncolytic vaccinia virus (OVV) has demonstrated appropriate safety profiles for clinical development. Although designed to kill cancer cells efficiently, OVV sensitivity varies in individual cancers, and predictive biomarkers of therapeutic responses have not been identified. Here we found that OVV...

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Bibliographic Details
Main Authors: Kosuke Horita, Hajime Kurosaki, Motomu Nakatake, Nozomi Kuwano, Tetsuro Oishi, Hiroaki Itamochi, Sho Sato, Hiromichi Kono, Mai Ito, Kosei Hasegawa, Tasuku Harada, Takafumi Nakamura
Format: Article
Language:English
Published: Elsevier 2019-06-01
Series:Molecular Therapy: Oncolytics
Online Access:http://www.sciencedirect.com/science/article/pii/S2372770519300336

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http://www.sciencedirect.com/science/article/pii/S2372770519300336

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