Cysteine mutants of human apolipoprotein A-I: a study of secondary structural and functional properties

Apolipoprotein A-IMilano (A-IM) (R173C), a natural mutant of human apolipoprotein A-I (apoA-I), and five other cysteine variants of apoA-I at residues 52 (S52C), 74 (N74C), 107 (K107C), 129 (G129C), and 195 (K195C) were generated. Cysteine residues were incorporated in each of the various helices at...

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Bibliographic Details
Main Authors: Xuewei Zhu, Gang Wu, Wuwei Zeng, Hong Xue, Baosheng Chen
Format: Article
Language:English
Published: Elsevier 2005-06-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520330352