Comparing artificial neural networks, general linear models and support vector machines in building predictive models for small interfering RNAs.

<h4>Background</h4>Exogenous short interfering RNAs (siRNAs) induce a gene knockdown effect in cells by interacting with naturally occurring RNA processing machinery. However not all siRNAs induce this effect equally. Several heterogeneous kinds of machine learning techniques and feature...

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Bibliographic Details
Main Authors: Kyle A McQuisten, Andrew S Peek
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-10-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19847297/pdf/?tool=EBI