Oxidative stress in peripheral blood mononuclear cells from patients with Parkinson's disease: Negative correlation with levodopa dosage

Oxidative stress in peripheral blood mononuclear cells from patients with Parkinson's disease: Negative correlation with levodopa dosage

Oxidative stress, resulting from the imbalance between reactive oxygen species (ROS) formation and antioxidant defenses, plays a major role in the pathogenesis of Parkinson's disease (PD). However, the contribution of levodopa (LD) therapy to oxidative damage is still debated. We investigated o...

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Bibliographic Details
Main Authors: Alessandro Prigione, Barbara Begni, Alessio Galbussera, Simone Beretta, Laura Brighina, Rosanna Garofalo, Simona Andreoni, Roberto Piolti, Carlo Ferrarese
Format: Article
Language:English
Published: Elsevier 2006-07-01
Series:Neurobiology of Disease
Subjects:
Parkinson's disease
Levodopa
Oxidative stress
PBMC
Reactive oxygen species
Glutathione reductase
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996106000179

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http://www.sciencedirect.com/science/article/pii/S0969996106000179

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