One-pot multicomponent nitro-Mannich reaction using a heterogeneous catalyst under solvent-free conditions

An environmentally-friendly, one-pot multicomponent reaction of various aldehydes, amines and nitroalkanes for the synthesis of β-nitroamines is here described. Amberlyst A-21 supported CuI was found to be a highly efficient novel heterogeneous catalyst for the three-component nitro-Mannich reaction...

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Bibliographic Details
Main Authors: Giovanna Bosica, Ramon Zammit
Format: Article
Language:English
Published: PeerJ Inc. 2018-06-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/5065.pdf