Chitin protects the gut epithelial barrier in a protochordate model of DSS-induced colitis

Chitin protects the gut epithelial barrier in a protochordate model of DSS-induced colitis

The gastrointestinal tract of Ciona intestinalis, a solitary tunicate that siphon-filters water, shares similarities with its mammalian counterpart. The Ciona gut exhibits other features that are unique to protochordates, including certain immune molecules, and other characteristics, e.g. chitin-ric...

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Bibliographic Details
Main Authors: Assunta Liberti, Ivana Zucchetti, Daniela Melillo, Diana Skapura, Yoshimi Shibata, Rosaria De Santis, Maria Rosaria Pinto, Gary W. Litman, Larry J. Dishaw
Format: Article
Language:English
Published: The Company of Biologists 2018-01-01
Series:Biology Open
Subjects:
Inflammatory bowel disease
DSS-induced colitis
Ciona intestinalis
Chitin-rich mucus
VCBPs
Host-microbes interaction
Online Access:http://bio.biologists.org/content/7/1/bio029355

Internet

http://bio.biologists.org/content/7/1/bio029355

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