Development of Novel Promiscuous Anti-Chemokine Peptibodies for Treating Autoimmunity and Inflammation

Development of Novel Promiscuous Anti-Chemokine Peptibodies for Treating Autoimmunity and Inflammation

Chemokines and their receptors play critical roles in the progression of autoimmunity and inflammation. Typically, multiple chemokines are involved in the development of these pathologies. Indeed, targeting single chemokines or chemokine receptors has failed to achieve significant clinical benefits...

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Bibliographic Details
Main Authors: Michal Abraham, Hanna Wald, Dalit Vaizel-Ohayon, Valentin Grabovsky, Zohar Oren, Arnon Karni, Lola Weiss, Eithan Galun, Amnon Peled, Orly Eizenberg
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-11-01
Series:Frontiers in Immunology
Subjects:
chemokines
autoimmunity
inflammation
phage display
peptibodies
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01432/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01432/full

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