DET1-mediated degradation of a SAGA-like deubiquitination module controls H2Bub homeostasis

DET1-mediated degradation of a SAGA-like deubiquitination module controls H2Bub homeostasis

DE-ETIOLATED 1 (DET1) is an evolutionarily conserved component of the ubiquitination machinery that mediates the destabilization of key regulators of cell differentiation and proliferation in multicellular organisms. In this study, we provide evidence from Arabidopsis that DET1 is essential for the...

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Main Authors: Amr Nassrallah, Martin Rougée, Clara Bourbousse, Stephanie Drevensek, Sandra Fonseca, Elisa Iniesto, Ouardia Ait-Mohamed, Anne-Flore Deton-Cabanillas, Gerald Zabulon, Ikhlak Ahmed, David Stroebel, Vanessa Masson, Berangere Lombard, Dominique Eeckhout, Kris Gevaert, Damarys Loew, Auguste Genovesio, Cecile Breyton, Geert De Jaeger, Chris Bowler, Vicente Rubio, Fredy Barneche
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-09-01
Series:eLife
Subjects:
epigenome
Histone H2B deubiquitination
light signaling
DET1
SAGA complex
photomorphogenesis
Online Access:https://elifesciences.org/articles/37892

Internet

https://elifesciences.org/articles/37892

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