Mechanistic approach of the inhibitory effect of chrysin on inflammatory and apoptotic events implicated in radiation-induced premature ovarian failure: Emphasis on TGF-β/MAPKs signaling pathway

Mechanistic approach of the inhibitory effect of chrysin on inflammatory and apoptotic events implicated in radiation-induced premature ovarian failure: Emphasis on TGF-β/MAPKs signaling pathway

Radiotherapy is one of the most relevant treatment modalities for various types of malignancies. However, it causes premature ovarian failure (POF) and subsequent infertility in women of reproductive age; hence urging the development of effective radioprotective agents. Chrysin, a natural flavone, p...

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Bibliographic Details
Main Authors: Eman M. Mantawy, Riham S. Said, Amal Kamal Abdel-Aziz
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Ovarian failure
Radiotherapy
Chrysin
Apoptosis
Inflammation
MAPKs
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332218360931

Internet

http://www.sciencedirect.com/science/article/pii/S0753332218360931

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