Induction of endoplasmic reticulum calcium pump expression during early leukemic B cell differentiation

Induction of endoplasmic reticulum calcium pump expression during early leukemic B cell differentiation

Abstract Background Endoplasmic reticulum (ER) calcium storage and release play important roles in B lymphocyte maturation, survival, antigen-dependent cell activation and immunoglobulin synthesis. Calcium is accumulated in the endoplasmic reticulum (ER) by Sarco/Endoplasmic Reticulum Calcium ATPase...

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Bibliographic Details
Main Authors: Lamia Aït Ghezali, Atousa Arbabian, Hervé Roudot, Jean-Philippe Brouland, Fanny Baran-Marszak, Evelyn Salvaris, Andrew Boyd, Hans G. Drexler, Agnes Enyedi, Remi Letestu, Nadine Varin-Blank, Bela Papp
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Pre-B acute lymphoblastic leukemia
Phorbol ester
Endoplasmic reticulum
SERCA
Calcium transport
Online Access:http://link.springer.com/article/10.1186/s13046-017-0556-7

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http://link.springer.com/article/10.1186/s13046-017-0556-7

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