USP13 mediates PTEN to ameliorate osteoarthritis by restraining oxidative stress, apoptosis and inflammation via AKT-dependent manner
Osteoarthritis is a chronic, systemic and inflammatory disease. However, the pathogenesis and understanding of RA are still limited. Ubiquitin-specific protease 13 (USP13) belongs to the deubiquitinating enzyme (DUB) superfamily, and has been implicated in various cellular events. Nevertheless, its...
Main Authors: | Jianming Huang, Zhiyang Ye, Jun Wang, Qichuan Chen, Danlei Huang, Haoyuan Liu |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-01-01
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Series: | Biomedicine & Pharmacotherapy |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0753332220312828 |
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